December 11-13, 20120 - Heidelberg, German Cancer Research Center (DKFZ)
Program of Medical Genome Research

The Program of Medical Genome Research is a large-scale biomedical research program in extension of the National Genome Research Network (NGFN). 200 million Euros have been earmarked for the Program for the years 2008 to 2013 by the German Federal Ministry of Education and Research (BMBF). In the NGFN-Plus sub-program, 26 Integrated Genome Research Networks (IG) focus on the systematic analysis of the molecular basis and on the combating of diseases that are central to health policy, eight IGs could be completed in 2011. In NGFN-Transfer, eight Innovation Alliances (IA) transferred results from medical genome research into medical and industrial application. All NGFN-Transfer projects will be completed by mid-2012.
In the program, researchers at more than 60 locations throughout Germany cooperate in the interdisciplinary organized research consortia that connect universities, large research institutes, clinics, and small and medium-sized enterprises. Efficient utilization of research capacities and of the latest technologies on the highest scientific level allows the investigation of the molecular cause of diseases with a high incidence and a particular importance in public health. A central aim is to promote the development of innovative methods for prevention, diagnosis, and therapy of major diseases. The large repertoire of technologies includes functional and structural genomics, proteomics, epigenetics, systems biology, bioinformatics, genetic epidemiology, genotyping, (next-generation) sequencing and proof-of-principle approaches such as animal models.

Please see the NGFN Webpage for further information:

List of Integrated Genome Research Networks in NGFN-Plus

Integrated Genome
Research Network

Coordination Institution
Brain Tumor Network

Prof. Dr. Peter

DKFZ, Heidelberg

Cellular Systems Genomics in        Health and Disease*

PD Dr. Stefan Wiemann
DKFZ, Heidelberg
Deciphering Oncogene Dependencies

Prof. Dr. Roman Thomas

Universität Köln
Epilepsy and Migraine Integrated Network (EMINet)

Prof. Dr. Christian
Universität Ulm

From Disease Genes to
Protein Pathways (DiGTOP)

Prof. Dr. Wolfgang
Helmholtz Zentrum München
Functional and Translational Genomics of Acute Leukemias

Prof. Dr. Christian Hagemeier Charité Berlin
Functional Genomics of Parkinson

Prof. Dr. Thomas Gasser Universität Tübingen
Gene Identification and Functional Analyses in Alzheimer´s Disease

Prof. Dr. Matthias Riemenschneider Universitätsklinikum des Saarlandes, Homburg/Saar
Genetics of Alcohol Addiction

Prof. Dr. Rainer

Zentralinstitut für Seelische Erkrankungen

Genetics of Heart Failure

Prof. Dr. Hugo Katus Universität Heidelberg
Genome Research Network in Pancreatic Cancer

Prof. Dr. Thomas M. Gress Universität Marburg
Genomics of Atherosclerosis Prof. Dr. Heribert Schunkert

Universität Lübeck
German Mental Retardation
Network (MRNET)*

Prof. Dr. André Reis Universität Erlangen
German Mouse Clinic -

Prof. Dr. Martin Hrabé
de Angelis

Helmholtz Zentrum München
Integrated Genome Network
of Prostate Cancer*

PD Dr. Holger Sültmann DKFZ, Heidelberg
Integrated Genomic Investigation
of Colorectal Carcinoma*

Prof. Dr. Kari Hemminki DKFZ, Heidelberg
MHC Haplotype Sequencing:
An Intergrated Approach to Common Disease*

Dr. Margret Hoehe MPI für molekulare Genetik Berlin
Modifiers of Intestinal Tumor Formation and Progression*

Prof. Dr.  Bernhard Herrmann MPI für molekulare Genetik Berlin
Molecular Causes of Major Mood Disorders and Schizophrenia (MooDS)

Prof. Dr. Markus Nöthen Universität Bonn
Molecular Mechanisms in Obesity Prof. Dr. Johannes Hebebrand

Universität Duisburg-Essen
Neuroblastoma Genome
Interaction Network

Prof. Dr. Angelika
Universität Duisburg-Essen
Neurodegenerative Diseases Networks (NeuroNet)*

Prof. Dr. Erich Wanker Max-Delbrück-Zentrum für Molekulare Medizin Berlin
Pathogenic Role of mi-RNA in Herpes-Infections

Prof. Dr. Juergen G.
LMU München
RNomics in Infections

Prof. Dr. Jürgen Brosius Universität Münster
Systematic Genomics of Chronic Inflammatory Barrier Diseases

Prof. Dr. Stefan
Universität Kiel
Systems Biology of Genetic
Diseases (Mutanom)*
Prof. Dr. Hans Lehrach;
PD Dr. Bodo Lange
MPI für molekulare Genetik Berlin

List of Innovation Alliances in NGFN-Transfer*

Integrated Genome
Research Network

Coordination Institution
Anti-malarial Agents Dr. Birte Sönnichsen

Cenix Bioscience Dresden
Breast Cancer Kit

Prof. Dr. Jan G. Hengstler Leibniz Institut für Arbeitsphysiologie an der Universität Dortmund

Heart Failure Therapy

Prof. Dr. Markus Hecker

Universität Heidelberg
Metabolomic signatures of heart failure

Prof. Dr. Hugo Katus Universität Heidelberg
New Tools for the Prevention of Cardiovascular Diseases and Disorders in Chronic Kidney Disease

Prof. Dr.
Joachim Jankowski
Charité Berlin
Protein analysis of formalin-fixed tumor (FFPE) samples

Prof. Dr. Karl-Friedrich Becker

Technische Universität München
Subgenome Fractionation for High Throughput Sequencing

Dr. Benjamin Meder Universitätsklinikum, Heidelberg
Whole genome and transcriptome amplification in large biobanks

Prof. Dr. Dr. H.-Erich Wichmann;
Dr. Christian Korfhage
Helmholtz Zentrum München;
Qiagen GmbH Hilden

*completed projects