December 11-13, 20120 - Heidelberg, German Cancer Research Center (DKFZ)
Tuesday, December 11, 2012 
Satellite Symposia - Krehl Klinik Auditorium (INF 410) 
12:00 - 2:00 pm
Small RNAs
(Org. Jürgen Haas and Jürgen Brosius)
Download Program Satellite Symposium Small RNAs
2:00 - 2:30 pm
Coffee Break
2:30 - 4:00 pm
Next-Generation Sequencing
(Org. Stefan Wiemann and Bernd Timmermann)
Download Program Satellite Symposium NGS
4:00 - 4:30 pm
Coffee Break
Welcome- DKFZ Communication Center 
4.30– 5.00 pm
Wolfgang Wurst, Helmholtz Zentrum Munich, Germany, Speaker Project Committee of NGFN-Plus / NGFN-Transfer in the Program of Medical Genome Research

N.N., Federal Minstry of Education and Research, Germany

Christof von Kalle, National Center for Tumor Diseases (NCT)/ German Cancer Research Center (DKFZ), Heidelberg, Germany
Symposium I: International Projects in the Program of                                                      Medical Genome Research 
5.00 – 5.30 pm
International Cancer Genome Consortium (ICGC)
Michael Taylor, The Hospital for Sick Children, Toronto, Canada
5.30 – 6.00 pm
International Cancer Genome Consortium (ICGC)
Peter Lichter, German Cancer Research Center, Heidelberg, Germany
Novel findings in pediatric brain tumors revealed by high resolution genome, methylome and transcriptome analyses
6.00 – 6.30 pm
International Cancer Genome Consortium (ICGC)
Matthew Meyerson, Dana Farber Cancer Institute, Boston, USA
Genome Alterations in Human Lung Cancers
6.30 – 7.00 pm
1000 Genomes Project
Hans Lehrach, MPI for Molecular Genetics, Berlin, Germany
1000 Genomes Project – An integrated map of genetic variation
7.00 pm
Wednesday, December 12, 2012  
Symposium II: International Projects in Genome Research 
 9.00 – 9.30 am
John Blangero, Texas Biomedical Research Institute, San Antonio, USA
Identification of Complex Disease Genes Using Whole Genome Sequencing in Large Pedigrees
 9.30 – 10.00 am
Joris A. Veltman, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
De novo diagnostics in patients with intellectual disability
10.00 – 10.30 am
Alzheimer’s Disease Genetics Consortium (ADGC)
Gerard D. Schellenberg, University of Pennsylvania School of Medicine, Philadelphia, USA
Neurodegenerative disease genetics; GWAS, exomes and beyond
10.30 – 11.00 am
Coffee Break
11.00 – 11.30 am
International Human Epigenome Consortium (IHEC)
Peter Jones, USC Norris Comprehensive Cancer Center, Los Angeles, USA
The Cancer Epigenome
11.30 – 12.00 pm
International Human Epigenome Consortium (IHEC)
Jörn Walter, Saarland University, Germany
Control of DNA-methylation in development
12.00 – 2.00 pm

Lunch Break and Poster Session I
12.00 - 01.00 pm odd numbers
01.00 - 02.00 pm even numbers

Company Satellite Sessions

Affymetrix UK Ltd
Caliper a PerkinElmer Company
Illumina UK Ltd
Bio-Rad Laboratories GmbH

2.00 – 2.30 pm
International Knockout Mouse Consortium / EUCOMM
Wolfgang Wurst, Helmholtz Zentrum Munich, Germany
International Mouse Knock-out Consortium: Resource to functionally validate all genes
2.30 – 3.00 pm
The International Mouse Phenotyping Consortium, EUMODIC and INFRAFRONTIER
Martin Hrabe de Angelis, Helmholtz Zentrum Munich, Germany
Creating a comprehensive encyclopedia of mammalian gene function
3.00 – 3.30 pm
Matthias Mann, Max Planck Institute for Biochemistry, Munich, Germany
High resolution, quantitative mass spectrometry combines proteomics and genomics
   3.30 – 4.00 pm         Coffee Break
Symposium III: Genomics of Common Disease I 
4.00 – 4.15 pm
André Reis, University Erlangen-Nuremberg, Germany
Range of genetic mutations associated with severe non-syndromic sporadic intellectual disability: An exome sequencing study
4.15 – 4.30 pm
Vanessa Nieratschker, Central Institute for Mental Health, Mannheim, Germany
Pre-, peri- and postnatal stress in human and non-human off-spring: A convergent approach to study genetic and epigenetic impact on depression
4.30 – 4.45 pm
Andre Franke, University Hospital Schleswig-Holstein, Kiel, Germany
Host-microbe interactions shape genetic risk for inflammatory bowel disease
4.45 - 5.00 pm
Robert Häsler, Christian Albrechts University of Kiel, Germany
Mapping the functional epigenome of Ulcerative Colitis in monozygotic twins
5.00 - 5.30 pm
Coffee Break
5.30 - 5.45 pm
Anke Hinney, University of Duisburg-Essen, Germany
Childhood ADHD and obesity: Evidence for a common genetic link
5.45 - 6.00 pm
Ralf Herwig, Max Planck Institute for Molecular Genetics, Berlin, Germany
An integrated catalogue of genome, methylome and gene expression variations in colon cancer

Evening Lecture 
6.00 - 7.00 pm

Randolph Nesse, The University of Michigan, Ann Arbor, USA

Evolutionary Medicine and Molecular Medicine: Synergistic Siblings

7.00 - 10.00 pm
Get-Together (Wine, Cheese, Live Music)

Thursday, December 13, 2012  
Symposium IV: Genomics of Common Disease II 
9.00 - 9.30 am
Keynote Hugo A. Katus, Heidelberg University Hospital, Germany
Innovations in translational research – Successes of NGFN
9.30 - 9.45 am
Christina Loley, University of Lübeck, Germany
Association of X-chromosomal variants with coronary heart disease: Results from a meta-analysis
9.45 - 10.00 am
Martin Peifer, University of Cologne, Germany
Toward a novel genomics-based taxonomy of lung cancer: The Clinical Lung Cancer Genome Project
10.00 - 10.15 am
Christel Herold-Mende, University of Heidelberg, Germany
Aberrant self-renewal and quiescence contribute to Glioblastoma aggressiveness
10.15 - 10.45 am
Coffee Break
Symposium V: Functional Genomics 
10.45 - 11.00 am
Jan Korbel, The European Molecular Biology Laboratory, Heidelberg, Germany
Genome sequencing of childhood medulloblastoma brain tumors links chromothripsis with TP53 mutations
11.00 - 11.15 am
Gerrit Erdmann, German Cancer Research Center, Heidelberg, Germany
Secretion of Wnts is required for Wnt/ß-catenin pathway activity in colorectal cancer (CRC) despite APC or ß-catenin mutations    
11.15 - 11.30 am
Sven Lindner, University Hospital Essen, Germany
LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression
11.30 - 11.45 am
Sören Westphal, University Clinic Ulm, Germany
Human BCL2-associated athanogene 3 (BAG3) mutations lead to dilated cardiomyopathy in zebrafish   
11.45 - 12.00 pm
Zouhair Aherrahrou, University of Lübeck, Germany
Cyp17a1 deficient mice display increased body weight, visceral/subcutaneous fat deposition and altered lipid metabolism
12.00 - 2.00 pm

Lunch Break and Poster Session II
12.00 – 01.00 pm odd numbers
01.00 – 02.00 pm even numbers

Company Satellite Sessions

Life Technologies GmbH 
Roche Diagnostics Deutschland GmbH

Nanostring Technologies, Inc.

2.00 – 2.15 pm
Ceremony: "Annemarie Poustka Poster Award 2012"
sponsored by Roche Diagnostics Deutschland GmbH
Christine Kuch, Roche Diagnostics Deutschland GmbH
Hugo A. Katus, Heidelberg University Clinics, Project Committee of NGFN?Plus / NGFN?Transfer in the Program of Medical Genome Research
Symposium VI: Personalized Medicine 
2.15 – 2.45 pm
Keynote: Rudi Balling, Luxembourg Centre for Systems Biomedicine, Luxembourg
Systems approaches to Parkinson´s disease
2.45 - 3.00 pm
Nicole Teichmann, University Hospital rechts der Isar, Munich, Germany
A promising therapy strategy for PDAC: MEK1/2 inhibition with the novel chemotherapeutic drug BAY 86-9766 (RDEA119)   
3.00 – 3.15 pm
Margret Hoehe, Max Planck Institute for Molecular Genetics, Berlin, Germany
Haplotype-resolving multiple human genomes: Key to personalized medicine and genome biology
3.15 – 3.30 pm
Jeanette Erdmann, University of Lübeck, Germany
The risk of myoacardial infarction is increased by digenic mutation in GUCY1A3 and CCT7 -  identified by exome sequencing in an extended family
3.30 – 3.45 pm
Brajesh Kaistha, University of Marburg, Germany
High-throughput cell-based assays identify Placenta-specific 8 (Plac8; Onzin) as a key regulator of proliferation and survival in pancreatic cancer cells
3.45 – 4.00 pm
Concluding Remarks: Markus Nöthen, Friedrich-Wilhelms University, Bonn, Speaker Project Committee of NGFN-Plus / NGFN-Transfer in the Program of Medical Genome Research
4.00 - 4.30 pm
Closing Coffee
Download program here