Program of Medical Genome Research
The Program of Medical Genome Research is a large-scale biomedical research program in extension of the National Genome Research Network (NGFN). 156 million Euros have been earmarked for the Program for the years 2008 to 2013 by the German Federal Ministry of Education and Research (BMBF). In the NGFN-Plus sub-program, 26 Integrated Genome Research Networks (IG) focus on the systematic analysis of the molecular basis and on the combating of diseases that are central to health policy. In NGFN-Transfer, eight Innovation Alliances (IA) transfer results from medical genome research into medical and industrial application. The majority of the consortia started their activities in June 2008.
In the program, researchers at more than 60 locations throughout Germany cooperate in the interdisciplinary organized research consortia that connect universities, large research institutes, clinics, and small and medium-sized enterprises. Efficient utilization of research capacities and of the latest technologies on the highest scientific level allows the investigation of the molecular cause of diseases with a high incidence and a particular importance in public health. A central aim is to promote the development of innovative methods for prevention, diagnosis, and therapy of major diseases. The large repertoire of technologies includes functional and structural genomics, proteomics, epigenetics, systems biology, bioinformatics, genetic epidemiology, genotyping, (next-generation) sequencing and proof-of-principle approaches such as animal models.
List of Integrated Genome Research Networks in NGFN-Plus
| Integrated Genome Research Network |
Coordination | Institution |
| Brain Tumor Network |
Prof. Peter Lichter |
DKFZ, Heidelberg |
| Cellular Systems Genomics in Health and Disease |
PD Dr. Stefan Wiemann |
DKFZ, Heidelberg |
| Deciphering Oncogene Dependencies |
PD Dr. Roman Thomas |
MPI für neurologische Forschung Köln |
| Epilepsy and Migraine Integrated Network (EMINet) |
Prof. Christian Kubisch |
Universität Köln |
| From Disease Genes to Protein Pathways (DiGTOP) |
Prof. Wolfgang Wurst |
Helmholtz Zentrum München |
| Functional and Translational Genomics of Acute Leukemias |
Prof. Christian Hagemeier | Charité Berlin |
| Functional Genomics of Parkinson |
Prof. Thomas Gasser | Universität Tübingen |
| Gene Identification and Functional Analyses in Alzheimer´s Disease |
PD Dr. Matthias Riemenschneider | Universitätsklinikum des Saarlandes, Homburg/Saar |
| Genetics of Alcohol Addiction |
Prof. Rainer Spanagel |
Zentralinstitut für Seelische Erkrankungen |
| Genetics of Heart Failure |
Prof. Hugo Katus | Universität Heidelberg |
| Genome Research Network in Pancreatic Cancer |
Prof. Thomas M. Gress | Universität Marburg |
| Genomics of Atherosclerosis | Prof. Heribert Schunkert |
Universität Lübeck |
| German Mental Retardation Network (MRNET) |
Prof. André Reis | Universität Erlangen |
| German Mouse Clinic - Deciphering |
Prof. Martin Hrabé de Angelis |
Helmholtz Zentrum München |
| Integrated Genome Network of Prostate Cancer |
PD Dr. Holger Sültmann | DKFZ, Heidelberg |
| Integrated Genomic Investigation of Colorectal Carcinoma |
Prof. Kari Hemminki | DKFZ, Heidelberg |
| MHC Haplotype Sequencing: An Intergrated Approach to Common Disease |
Dr. Margret Hoehe | MPI für molekulare Genetik Berlin |
| Modifiers of Intestinal Tumor Formation and Progression |
Prof. Bernhard Herrmann | MPI für molekulare Genetik Berlin |
| Molecular Causes of Major Mood Disorders and Schizophrenia (MooDS) |
Prof. Markus Nöthen | Universität Bonn |
| Molecular Mechanisms in Obesity | Prof. Johannes Hebebrand |
Universität Duisburg-Essen |
| Neuroblastoma Genome Interaction Network |
Prof. Angelika Eggert |
Universität Duisburg-Essen |
| Neurodegenerative Diseases Networks (NeuroNet) |
Prof. Erich Wanker | Max-Delbrück-Zentrum für Molekulare Medizin Berlin |
| Pathogenic Role of mi-RNA in Herpes-Infections |
Prof. Juergen G. Haas |
LMU München |
| RNomics in Infections |
Prof. Jürgen Brosius | Universität Münster |
| Systematic Genomics of Chronic Inflammatory Barrier Diseases |
Prof. Stefan Schreiber |
Universität Kiel |
| Systems Biology of Genetic Diseases (Mutanom) | Prof. Hans Lehrach | MPI für molekulare Genetik Berlin |
List of Innovation Alliances in NGFN-Transfer
| Integrated Genome Research Network |
Coordination | Institution |
| Anti-malarial Agents | Dr. Birte Sönnichsen |
Cenix Bioscience Dresden |
| Breast Cancer Kit |
Prof. Jan G. Hengstler | Leibniz Institut für Arbeitsphysiologie an der Universität Dortmund |
| Heart Failure Therapy |
Prof. Markus Hecker |
Universität Heidelberg |
| Metabolomic signatures of heart failure |
Prof. Hugo Katus | Universität Heidelberg |
| New Tools for the Prevention of Cardiovascular Diseases and Disorders in Chronic Kidney Disease |
PD Dr. Joachim Jankowski | Charité Berlin |
| Protein analysis of formalin-fixed tumor (FFPE) samples |
PD Dr. Karl-Friedrich Becker |
Technische Universität München |
| Subgenome Fractionation for High Throughput Sequencing |
Dr. Bernhard Korn | DKFZ, Heidelberg |
| Whole genome and transcriptome amplification in large biobanks |
Prof. H.-Erich Wichmann; Dr. Christian Korfhage |
Helmholtz Zentrum München; Qiagen GmbH Hilden |
