Preliminary Program
Thursday, November 26, 2009
1:00 - 4:00 pm
4:00 - 4:30 pm
Coffee Break
4:30 - 6:30 pm
7:00 pm
Supper
Friday, November 27, 2009
Symposium I: Genomics of Common Disease
8.30 - 9.15 am
Keynote: Heribert Schunkert, University Clinics Lübeck, Germany
Genetics of myocardial infarction
9.15 - 9.30 am
Christian Gieger, Helmholtz Zentrum München, Germany
The role of genetically determined metabotypes in the genetics of complex traits and polygenic disorders.
The role of genetically determined metabotypes in the genetics of complex traits and polygenic disorders.
9.30 - 9.45 am
Anke Hinney, University Duisburg-Essen, Germany
Two new loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early onset extreme obesity in French and German study groups
Two new loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early onset extreme obesity in French and German study groups
9.45 - 10.00 am
Sven Cichon, Institute of Human Genetics, University of Bonn, Gemany
Genome-wide survey implicates CNVs in early-onset bipolar disorder
Genome-wide survey implicates CNVs in early-onset bipolar disorder
10.00 - 10.15 am
Andre Franke, Christian-Albrechts-University zu Kiel, Germany
Whole-genome, -exome, and targeted resequencing approaches to identify the remaining genetic heritability in Crohn’s disease
Whole-genome, -exome, and targeted resequencing approaches to identify the remaining genetic heritability in Crohn’s disease
10.15 - 10.30 am
Margret Hoehe, Max Planck Institute for Molecular Genetics, Berlin, Germany
MHC Haplotype Sequencing: An Integrated Approach to Common Disease
MHC Haplotype Sequencing: An Integrated Approach to Common Disease
10.30 - 11.00 am
Coffee Break
Welcome
11.00 - 11.30
Martin Hrabé de Angelis,
Helmholz Zentrum München, Germany, Speaker Project Committee of
NGFN-Plus / NGFN-Transfer in the Program of Medical Genome Research
Helge Braun (MdB), Parlamentarischer Staatssekretär im Bundesministerium für Bildung und Forschung
Hans Lehrach, Max Planck Institute for Molecular Genetics, Berlin, Germany
Symposium II: Genomics of Sporadic Cancer
11:30 - 12:15 pm
Keynote: Ivo Gut, CEA/ Institut de Génomique-Centre National de Génotypage, Evry, France
From genome-wide association studies to whole-genome sequencing in cancer
From genome-wide association studies to whole-genome sequencing in cancer
12:15 - 12:30 pm
Vegi M. Naidu, LMU, Munich, Germany
AML1-ETO collaborates with the HOX Gene Co-Factor, MEIS1 in inducing acute leukemia in the mouse bone marrow transplantation model
AML1-ETO collaborates with the HOX Gene Co-Factor, MEIS1 in inducing acute leukemia in the mouse bone marrow transplantation model
12:30 - 12:45 pm
Özgür Sahin, German Cancer Research Center (DKFZ)
Modulation of ERBB receptor-driven cell invasion and proliferation by miR-200c via targeting PLC?1 and MIG-6 in breast cancer
Modulation of ERBB receptor-driven cell invasion and proliferation by miR-200c via targeting PLC?1 and MIG-6 in breast cancer
12:45 - 1:00 pm
Johannes Schulte, Universitätskinderklinik Essen, Germany
High ALK receptor tyrosine kinase expression prevail ALK mutation as a determining factor of an unfavorable phenotype in primary neuroblastoma
High ALK receptor tyrosine kinase expression prevail ALK mutation as a determining factor of an unfavorable phenotype in primary neuroblastoma
1:00 - 3:00 pm
Lunch Break and Poster Session I
1:00 - 3:00 pm
Symposium III: Animal, Cellular & Tissue Models
3:00 - 3:45 pm
Keynote: Mark Moore, Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK
Planning for the International Mouse Phenotyping Consortium
Planning for the International Mouse Phenotyping Consortium
3:45 - 4:00 pm
Bernhard G. Herrmann, Max Planck Institute for Molecular Genetics, Berlin, Germany
Identification of Modifiers of Intestinal Tumor Formation and Progression utilising mouse Chromosome Substitution Strains
Identification of Modifiers of Intestinal Tumor Formation and Progression utilising mouse Chromosome Substitution Strains
4:00 - 4:15 pm
Till Acker, Institute of Neuropathology,University Giessen, Germany
A hypoxic niche regulates tumor stem cells.
A hypoxic niche regulates tumor stem cells.
4:15 - 4:30 pm
Annette Schürmann, German Institute of Human Nutrition, Potsdam-Rehbrücke
The role of the GTPase Arfrp1 for lipid droplet formation and the regulation of lipolysis in adipose tissue
The role of the GTPase Arfrp1 for lipid droplet formation and the regulation of lipolysis in adipose tissue
4:30 - 4:45 pm
Guido Krebiehl, Hertie Institute for Clinical Brain Research - Center of Neurology, University of Tuebingen, Germany
Mitochondrial dysfunction and impaired lysosomal degradation due to loss of Parkinson's disease associated protein DJ-1
Mitochondrial dysfunction and impaired lysosomal degradation due to loss of Parkinson's disease associated protein DJ-1
4:45 - 5:15 pm
Coffee Break
Symposium IV: Systems Biology
5:15 - 6:00 pm
Keynote: Hans Westerhoff, University of Manchester, UK; Vrije Universiteit Amsterdam, NL
Integrative Genomics with a little help from its friend: from genes to function and back
Integrative Genomics with a little help from its friend: from genes to function and back
6:00 - 6:15 pm
Hans Lehrach, Max Planck Institute for Molecular Genetics, Berlin, Germany
The TREAT1000 project: a step towards an individualisation of medicine
The TREAT1000 project: a step towards an individualisation of medicine
6:15 - 6:30 pm
Bodo Lange, Max-Planck Institute for molecular Genetics, Berlin, Germany
A protein-protein interaction network links proteins of cell division pathways to their functional dysregulation in cancer
A protein-protein interaction network links proteins of cell division pathways to their functional dysregulation in cancer
6:30 - 6:45 pm
Björn Schwanhäusser, Max Delbrück Centrum Berlin, Germany
Genome-wide analysis of protein and mRNA half-lives reveals dynamic properties of mammalian gene expression
Genome-wide analysis of protein and mRNA half-lives reveals dynamic properties of mammalian gene expression
6:45 - 7:00 pm
Jörn Walter, Saarland University, Germany
From Epigenetics to Epigenomics - DNA-methylation patterns along human chromosomes
From Epigenetics to Epigenomics - DNA-methylation patterns along human chromosomes
Evening Lecture
7:00 - 8:00 pm
Jens Reich, Max-Delbrück Center, Berlin, Germany
Chimera Research in Development Biology - the Ethical Question
Chimera Research in Development Biology - the Ethical Question
8:00 - 10:00 pm
Get-together (Wine, Cheese, Music)
Saturday, November 28, 2009
Symposium V: New Technologies
9:00 - 9:30 am
Keynote I: Erich Wanker, Max-Delbrück Center for Molecular Medicine, Berlin, Germany
Protein folding and misfolding: a major challenge for modern disease research
Protein folding and misfolding: a major challenge for modern disease research
9:30 - 10:00 am
Keynote II: Jan Korbel, EMBL, Heidelberg, Germany
Structural Variations in the Genome- Using Next-Gen Sequencing to obtain insights into their Origins, Extent and Functional Impact
Structural Variations in the Genome- Using Next-Gen Sequencing to obtain insights into their Origins, Extent and Functional Impact
10:00 - 10:15 am
Hans-Jörg Warnatz, Max Planck Institute for Molecular Genetics, Berlin, Germany
Cell Array-Based Functional Analysis of Human Chromosome 21 Gene Promoters
Cell Array-Based Functional Analysis of Human Chromosome 21 Gene Promoters
10:15 - 10:30 am
Andreas Schlicker, Max Planck Institute for Informatics, Saarbrücken, Germany
Prioritizing Disease Genes from Association Studies using Functional Similarity
Prioritizing Disease Genes from Association Studies using Functional Similarity
10:30 - 10:45 am
Mihail Sarov, Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany
TransgeneOmics: a platform for systems wide protein function analysis in metazoans
TransgeneOmics: a platform for systems wide protein function analysis in metazoans
10:45 - 12:45 pm
Lunch Break and Poster Session II
10:45 - 12:45 pm
Company Satellite Lunch Sessions
Download program (PDF)
Download program (PDF)
Symposium VI: Transfer from Genomics to Application
12:45 - 1:30 pm
Keynote: Jörg Rademann, Leibniz-Institut für Molekulare Pharmakologie, Berlin, Germany
Virtual and dynamic small molecule screening in academic drug discovery
Virtual and dynamic small molecule screening in academic drug discovery
1:30 - 1:45 pm
Nikolaus Machuy, MPI for Infection Biology, Berlin, Germany
Human host cell factors crucial for influenza virus replication identified by genome-wide RNAi screen
Human host cell factors crucial for influenza virus replication identified by genome-wide RNAi screen
1:45 - 2:00 pm
Andreas Keller, Biomarker Discovery Center Heidelberg, Germany
Specific miRNA fingerprints in patients' blood samples as novel diagnostic tool
Specific miRNA fingerprints in patients' blood samples as novel diagnostic tool
2:00 - 2:15 pm
Ruprecht Kuner, German Cancer Research Center, Heidelberg
Genome-wide analysis of deregulated microRNAs in prostate cancer
Genome-wide analysis of deregulated microRNAs in prostate cancer
2:15 - 2:30 pm
Ulrike Korf, German Cancer Research Center, Heidleberg
Integration of genomic and proteomic data to unwire chemoresistance mechanisms
Integration of genomic and proteomic data to unwire chemoresistance mechanisms
2:30 - 2:45 pm
Patrick Linsel-Nitschke, University of Lübeck, Germany
Risk prediction of myocardial infarction using a weighted genetic score - the German MI Family Study
Risk prediction of myocardial infarction using a weighted genetic score - the German MI Family Study
2:45 - 3:00 pm
Ceremony: "Annemarie Poustka Poster Award of Medical Genome Research 2009" sponsored by Roche Diagnostics GmbH
Concluding Remarks:
Hugo A. Katus, Universitätsklinik Heidelberg, Speaker Project Committee of NGFN-Plus / NGFN-Transfer in the Program of Medical Genome Research
